Nemtabrutinib
As of the edition of 20 October 2026, Nemtabrutinib is a small molecule: in active development; acts on BTK.
Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.
The drug
- Status
- Active, 2029
- Kind
- Small molecule
- Registered trials
- 25, 0 stopped early
- Disease areas
- Blood and lymph; Cancer; Immune system; Heart and blood vessels; Pregnancy and women's health; Urinary and reproductive
US protection
No US approval on record.
With no US approval on record there are no listed US patents or exclusivities.
This is the US only.
Target
| Gene | Protein | UniProt |
|---|---|---|
| BTK | Tyrosine-protein kinase BTK | Q06187 |
Registered trials
| Phase | Trials | Completed | Active | Stopped early |
|---|---|---|---|---|
| Phase 1 | 11 | 9 | 2 | 0 |
| Phase 2 | 11 | 0 | 11 | 0 |
| Phase 3 | 3 | 0 | 3 | 0 |
| All trials | 25 |
Who ran its trials
| Company | Role | Years |
|---|---|---|
| Merck & Co. | Lead sponsor of trials | 2017 to now |