Drug

Omecamtiv mecarbil

As of the edition of 20 October 2026, Omecamtiv mecarbil is a small molecule: in active development; acts on MYH6, MYH7 and MYH7B and 4 more.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Active, 2026
Kind
Small molecule
Registered trials
15, 3 stopped early
Disease areas
Heart and blood vessels; Lungs and airways

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

1 company-target row on route B because of this drug.

Companies on route B for this drug

In the product

1 company-target row is on route B because of Omecamtiv mecarbil.

Targets

GeneProteinUniProt
MYH7BMyosin-7BA7E2Y1
MYL3Myosin light chain 3P08590
MYL2Myosin regulatory light chain 2, ventricular/cardiac muscle isoformP10916
MYL4Myosin light chain 4P12829
MYH7Myosin-7P12883
MYH6Myosin-6P13533
MYL7Myosin regulatory light chain 2, atrial isoformQ01449

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 13300
Phase 28602
Phase 34211
All trials15

Who ran its trials

CompanyRoleYears
CytokineticsLead sponsor of trials2005 to now