Drug

ONC-206

As of the edition of 20 October 2026, ONC-206 is a small molecule: in active development; acts on CLPP and DRD2.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Active, 2026
Kind
Small molecule
Registered trials
4, 0 stopped early
Disease areas
Cancer; Nervous system

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Targets

GeneProteinUniProt
DRD2Dopamine receptor D2P14416
CLPPATP-dependent Clp protease proteolytic subunit, mitochondrialQ16740

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 12020
Phase 22020
All trials4

Who ran its trials

CompanyRoleYears
Jazz PharmaceuticalsLead sponsor of trials2020 to now