Drug

Ontuxizumab

As of the edition of 20 October 2026, Ontuxizumab is an antibody: went quiet in 2020; acts on CD248.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2020
Kind
Antibody
Registered trials
5, 0 stopped early
Disease areas
Cancer; Blood and lymph; Heart and blood vessels; Immune system; Infections; Skin and connective tissue

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

2 companies on route A because of this drug.

Companies on route A for this drug

In the product

2 companies are on route A because of Ontuxizumab.

Target

GeneProteinUniProt
CD248EndosialinQ9HCU0

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 13300
Phase 22200
All trials5

Who ran its trials

CompanyRoleYears
MorphotekLead sponsor of trials2009 to now
EisaiLead sponsor of trials2011 to now