Drug

OPB 31121

As of the edition of 20 October 2026, OPB 31121 is a drug known only by a code name: went quiet in 2014; acts on STAT3.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2014
Kind
Code name only
Registered trials
5, 1 stopped early
Disease areas
Cancer; Blood and lymph; Immune system; Digestive system; Heart and blood vessels

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

1 company on route A because of this drug.

Companies on route A for this drug

In the product

1 company is on route A because of OPB 31121.

Target

GeneProteinUniProt
STAT3Signal transducer and activator of transcription 3P40763

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 14201
Phase 21100
All trials5

Who ran its trials

CompanyRoleYears
OtsukaLead sponsor of trials2007 to now
OtsukaLead sponsor of trials2011 to now