Drug

Perhexiline

As of the edition of 20 October 2026, Perhexiline is a small molecule: withdrawn from the market in 1985; acts on CPT1B, CPT2 and MTOR.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Withdrawn from market, 1985
Kind
Small molecule
Withdrawn from market
1 January 1985 (in some regions)
Registered trials
8, 2 stopped early
Disease areas
Heart and blood vessels; Inherited and neonatal

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Targets

GeneProteinUniProt
CPT2Carnitine O-palmitoyltransferase 2, mitochondrialP23786
MTORSerine/threonine-protein kinase mTORP42345
CPT1BCarnitine O-palmitoyltransferase 1, muscle isoformQ92523

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 25301
Phase 33101
All trials8