Drug

PF-03049423

As of the edition of 20 October 2026, PF-03049423 is a small molecule: stopped in 2013; acts on PDE5A.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2013
Kind
Small molecule
Registered trials
1, 1 stopped early
Disease areas
Heart and blood vessels; Nervous system

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

1 company on route A because of this drug.

Companies on route A for this drug

In the product

1 company is on route A because of PF-03049423.

Target

GeneProteinUniProt
PDE5AcGMP-specific 3',5'-cyclic phosphodiesteraseO76074

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 21001
All trials1

Who ran its trials

CompanyRoleYears
PfizerLead sponsor of trials2010 to now