Drug

Pozanicline

As of the edition of 20 October 2026, Pozanicline is a small molecule: stopped in 2011; acts on CHRNA4, CHRNA5 and CHRNA6.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2011
Kind
Small molecule
Registered trials
10, 4 stopped early
Disease areas
Mental health; Nervous system

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

6 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

6 company-target rows are on route A because of Pozanicline.

Targets

GeneProteinUniProt
CHRNA5Neuronal acetylcholine receptor subunit alpha-5P30532
CHRNA4Neuronal acetylcholine receptor subunit alpha-4P43681
CHRNA6Neuronal acetylcholine receptor subunit alpha-6Q15825

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 210604
All trials10

Who ran its trials

CompanyRoleYears
AbbottLead sponsor of trials2003 to now
AbbVieLead sponsor of trials2007 to now