Drug

RAF-265

As of the edition of 20 October 2026, RAF-265 is a small molecule: went quiet in 2013; acts on BRAF.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2013
Kind
Small molecule
Registered trials
2, 0 stopped early
Disease areas
Cancer; Skin and connective tissue

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

2 companies on route B because of this drug.

Companies on route B for this drug

In the product

2 companies are on route B because of RAF-265.

Target

GeneProteinUniProt
BRAFSerine/threonine-protein kinase B-rafP15056

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 11100
Phase 21100
All trials2

Who ran its trials

CompanyRoleYears
NovartisLead sponsor of trials2006 to now
PfizerLead sponsor of trials2011 to now