Drug

Razuprotafib

As of the edition of 20 October 2026, Razuprotafib is a small molecule: stopped in 2021; acts on PTPRB.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2021
Kind
Small molecule
Registered trials
8, 1 stopped early
Disease areas
Eye; Hormones; Heart and blood vessels; Infections; Lungs and airways

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

2 companies on route A because of this drug.

Companies on route A for this drug

In the product

2 companies are on route A because of Razuprotafib.

Target

GeneProteinUniProt
PTPRBReceptor-type tyrosine-protein phosphatase betaP23467

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 12200
Phase 26501
All trials8

Who ran its trials

CompanyRoleYears
Aerpio TherapeuticsLead sponsor of trials2012 to now
EyePoint PharmaceuticalsLead sponsor of trials2017 to now