Drug

Reparixin

As of the edition of 20 October 2026, Reparixin is a small molecule: stopped in 2024; acts on CXCR1 and CXCR2.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2024
Kind
Small molecule
Registered trials
14, 5 stopped early
Disease areas
Cancer; Lungs and airways; Skin and connective tissue; Infections; Heart and blood vessels; Hormones

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

2 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

2 company-target rows are on route A because of Reparixin.

Targets

GeneProteinUniProt
CXCR1C-X-C chemokine receptor type 1P25024
CXCR2C-X-C chemokine receptor type 2P25025

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 11100
Phase 28413
Phase 35302
All trials14

Who ran its trials

CompanyRoleYears
Dompé FarmaceuticiLead sponsor of trials2005 to now