Reserpine
As of the edition of 20 October 2026, Reserpine is a small molecule: marketed, first approved in 1982 (US); acts on SLC18A2; no US protection is listed.
Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.
The drug
- Status
- Marketed; latest approval 1988
- Kind
- Small molecule
- Brand name
- Serpasil
- First approved
- 1 January 1982 (US)
- Approvals on record
- 58 in 2 regions
- Holder of the most recent approval
- ETHYX PHARMACEUTICALS; 22 holders in all
- Withdrawn from market
- 1 January 1977 (in some regions)
- Registered trials
- 7, 2 stopped early
- Disease areas
- Heart and blood vessels; Chemically induced; Mental health; Nervous system; Injuries; Lungs and airways
US protection
No US protection is listed.
The FDA registers list no drug-substance patent or exclusivity that counts for this drug.
This is the US only.
Target
| Gene | Protein | UniProt |
|---|---|---|
| SLC18A2 | Synaptic vesicular amine transporter | Q05940 |
Registered trials
| Phase | Trials | Completed | Active | Stopped early |
|---|---|---|---|---|
| Phase not stated | 1 | 0 | 0 | 1 |
| Phase 1 | 2 | 0 | 0 | 1 |
| Phase 2 | 3 | 3 | 0 | 0 |
| Phase 3 | 1 | 1 | 0 | 0 |
| All trials | 7 |
Who has held its approvals
| Company | Role | Years |
|---|---|---|
| Bowman Pharmaceuticals | Acquired holder | 2003 to now |
| Cm Bundy | Acquired holder | 2003 to now |
| Panray Corp Sub Ormont Drug And Chemical | Acquired holder | 2003 to now |
| Vale Chemical | Acquired holder | 2003 to now |
| Sandoz | Acquired holder | 2005 to now |
| Ivax Pharmaceuticals Inc Sub Teva Pharmaceuticals | Acquired holder | 2009 to now |
| Cycle Pharmaceuticals | Acquired holder | 2015 to now |
| Amneal Pharmaceuticals | Later holder | |
| Bausch Health | Later holder | |
| Bristol Myers Squibb | Later holder | |
| Eli Lilly | Later holder | |
| Everylife | Later holder | |
| Hikma Pharmaceuticals | Later holder | |
| Lannett | Later holder | |
| Novartis | Applicant | |
| Vitarine Pharmaceuticals | Later holder |