Drug

Salirasib

As of the edition of 20 October 2026, Salirasib is a small molecule: went quiet in 2009; acts on HRAS, KRAS and NRAS.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2009
Kind
Small molecule
Registered trials
2, 0 stopped early
Disease areas
Cancer; Blood and lymph; Immune system; Lungs and airways

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

3 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

3 company-target rows are on route A because of Salirasib.

Targets

GeneProteinUniProt
NRASGTPase NRasP01111
HRASGTPase HRasP01112
KRASGTPase KRasP01116

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 11100
Phase 21100
All trials2

Who ran its trials

CompanyRoleYears
ConcordiaLead sponsor of trials2007 to now