Drug

Semaxanib

As of the edition of 20 October 2026, Semaxanib is a small molecule: stopped in 2013; acts on FLT1, FLT4 and KDR and 1 more.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2013
Kind
Small molecule
Registered trials
31, 4 stopped early
Disease areas
Cancer; Urinary and reproductive; Digestive system; Skin and connective tissue; Infections; Pregnancy and women's health

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

1 company-target row on route B because of this drug.

Companies on route B for this drug

In the product

1 company-target row is on route B because of Semaxanib.

Targets

GeneProteinUniProt
KITMast/stem cell growth factor receptor KitP10721
FLT1Vascular endothelial growth factor receptor 1P17948
FLT4Vascular endothelial growth factor receptor 3P35916
KDRVascular endothelial growth factor receptor 2P35968

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase not stated1100
Phase 110801
Phase 2181503
Phase 32100
All trials31

Who ran its trials

CompanyRoleYears
PfizerLead sponsor of trials1998 to now