Drug

Serlopitant

As of the edition of 20 October 2026, Serlopitant is a small molecule: stopped in 2020; acts on TACR1.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2020
Kind
Small molecule
Registered trials
12, 3 stopped early
Disease areas
Skin and connective tissue; Inherited and neonatal; Immune system; Chemically induced; Injuries; Lungs and airways

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

1 company on route A because of this drug.

Companies on route A for this drug

In the product

1 company is on route A because of Serlopitant.

Target

GeneProteinUniProt
TACR1Substance-P receptorP25103

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 29702
Phase 33201
All trials12

Who ran its trials

CompanyRoleYears
Yarrow BioscienceLead sponsor of trials2006 to now