Drug

SGI-1776

As of the edition of 20 October 2026, SGI-1776 is a small molecule: stopped in 2012; acts on PIM1, PIM2 and PIM3.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2012
Kind
Small molecule
Registered trials
2, 2 stopped early
Disease areas
Blood and lymph; Cancer; Immune system; Urinary and reproductive

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

3 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

3 company-target rows are on route A because of SGI-1776.

Targets

GeneProteinUniProt
PIM1Serine/threonine-protein kinase pim-1P11309
PIM3Serine/threonine-protein kinase pim-3Q86V86
PIM2Serine/threonine-protein kinase pim-2Q9P1W9

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 12002
All trials2

Who ran its trials

CompanyRoleYears
OtsukaLead sponsor of trials2009 to now