Drug

Tarextumab

As of the edition of 20 October 2026, Tarextumab is an antibody: stopped in 2017; acts on NOTCH2 and NOTCH3.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2017
Kind
Antibody
Registered trials
3, 1 stopped early
Disease areas
Cancer; Digestive system; Hormones; Lungs and airways

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

2 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

2 company-target rows are on route A because of Tarextumab.

Targets

GeneProteinUniProt
NOTCH2Neurogenic locus notch homolog protein 2Q04721
NOTCH3Neurogenic locus notch homolog protein 3Q9UM47

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 11100
Phase 22101
All trials3

Who ran its trials

CompanyRoleYears
Mereo BioPharmaLead sponsor of trials2010 to now