Drug

Tarloxotinib

As of the edition of 20 October 2026, Tarloxotinib is a small molecule: stopped in 2023; acts on EGFR, ERBB2 and ERBB3 and 1 more.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2023
Kind
Small molecule
Registered trials
4, 4 stopped early
Disease areas
Cancer; Lungs and airways

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

4 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

4 company-target rows are on route A because of Tarloxotinib.

Targets

GeneProteinUniProt
EGFREpidermal growth factor receptorP00533
ERBB2Receptor tyrosine-protein kinase erbB-2P04626
ERBB3Receptor tyrosine-protein kinase erbB-3P21860
ERBB4Receptor tyrosine-protein kinase erbB-4Q15303

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 24004
All trials4

Who ran its trials

CompanyRoleYears
Pathos AILead sponsor of trials2015 to now