Telaglenastat
As of the edition of 20 October 2026, Telaglenastat is a small molecule: stopped in 2022; acts on GLS.
Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.
The drug
- Status
- Stopped, 2022
- Kind
- Small molecule
- Registered trials
- 23, 4 stopped early
- Disease areas
- Cancer; Lungs and airways; Pregnancy and women's health; Urinary and reproductive; Blood and lymph; Immune system
US protection
No US approval on record.
With no US approval on record there are no listed US patents or exclusivities.
This is the US only.
Companies that need a new molecule because of this drug
1 company on route A because of this drug.
Companies on route A for this drug
In the product1 company is on route A because of Telaglenastat.
See the 1 company on route A for this drug, with the facts behind eachRequest access. Nothing is shown until you do.
Target
| Gene | Protein | UniProt |
|---|---|---|
| GLS | Glutaminase kidney isoform, mitochondrial | O94925 |
Registered trials
| Phase | Trials | Completed | Active | Stopped early |
|---|---|---|---|---|
| Phase 1 | 10 | 6 | 3 | 1 |
| Phase 2 | 13 | 5 | 4 | 3 |
| All trials | 23 |
Who ran its trials
| Company | Role | Years |
|---|---|---|
| Calithera Biosciences | Lead sponsor of trials | 2014 to now |