Drug

Telotristat

As of the edition of 20 October 2026, Telotristat is a small molecule: stopped in 2022; acts on TPH1 and TPH2.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2022
Kind
Small molecule
Registered trials
1, 1 stopped early
Disease areas
Cancer

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Targets

GeneProteinUniProt
TPH1Tryptophan 5-hydroxylase 1P17752
TPH2Tryptophan 5-hydroxylase 2Q8IWU9

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 21001
All trials1