Drug

Teniposide

As of the edition of 20 October 2026, Teniposide is a small molecule: marketed, first approved in 1992 (US); acts on TOP2A and TOP2B; no US protection is listed.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Marketed; latest approval 1992
Kind
Small molecule
Brand name
Vumon
First approved
14 July 1992 (US)
Approvals on record
1 in 1 region
Holder of the most recent approval
Hq Specialty Pharma
Registered trials
17, 0 stopped early
Disease areas
Cancer; Blood and lymph; Immune system; Lungs and airways; Infections

US protection

No US protection is listed.

The FDA registers list no drug-substance patent or exclusivity that counts for this drug.

This is the US only.

Companies that need a new molecule because of this drug

3 company-target rows on route B because of this drug.

Companies on route B for this drug

In the product

3 company-target rows are on route B because of Teniposide.

Targets

GeneProteinUniProt
TOP2ADNA topoisomerase 2-alphaP11388
TOP2BDNA topoisomerase 2-betaQ02880

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase not stated2000
Phase 27330
Phase 32110
Phase 46600
All trials17

Who has held its approvals

CompanyRoleYears
Hq Specialty PharmaAcquired holder2013 to now
Bristol Myers SquibbOriginator1992 to 2013