Tetrahydrouridine
As of the edition of 20 October 2026, Tetrahydrouridine is a small molecule: stopped in 2021; acts on CDA.
Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.
The drug
- Status
- Stopped, 2021
- Kind
- Small molecule
- Registered trials
- 13, 3 stopped early
- Disease areas
- Cancer; Blood and lymph; Lungs and airways; Skin and connective tissue; Digestive system; Immune system
US protection
No US approval on record.
With no US approval on record there are no listed US patents or exclusivities.
This is the US only.
Target
| Gene | Protein | UniProt |
|---|---|---|
| CDA | Cytidine deaminase | P32320 |
Registered trials
| Phase | Trials | Completed | Active | Stopped early |
|---|---|---|---|---|
| Phase 1 | 10 | 8 | 0 | 2 |
| Phase 2 | 3 | 1 | 1 | 1 |
| All trials | 13 |
Who ran its trials
| Company | Role | Years |
|---|---|---|
| EpiDestiny | Lead sponsor of trials | 2023 to now |