Drug

Tezosentan

As of the edition of 20 October 2026, Tezosentan is a small molecule: stopped in 2011; acts on EDNRA and EDNRB.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2011
Kind
Small molecule
Registered trials
5, 3 stopped early
Disease areas
Lungs and airways; Heart and blood vessels

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

1 company-target row on route B because of this drug.

Companies on route B for this drug

In the product

1 company-target row is on route B because of Tezosentan.

Targets

GeneProteinUniProt
EDNRBEndothelin receptor type BP24530
EDNRAEndothelin-1 receptorP25101

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 22002
Phase 33201
All trials5

Who ran its trials

CompanyRoleYears
Idorsia PharmaceuticalsLead sponsor of trials2003 to now