Tolrestat
As of the edition of 20 October 2026, Tolrestat is a small molecule: withdrawn from the market in 1996; acts on AKR1B1.
Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.
The drug
- Status
- Withdrawn from market, 1996
- Kind
- Small molecule
- Withdrawn from market
- 1 January 1996 (worldwide)
US protection
No US approval on record.
With no US approval on record there are no listed US patents or exclusivities.
This is the US only.
Target
| Gene | Protein | UniProt |
|---|---|---|
| AKR1B1 | Aldo-keto reductase family 1 member B1 | P15121 |