Drug

Trebananib

As of the edition of 20 October 2026, Trebananib is a drug: stopped in 2014; acts on ANGPT1 and ANGPT2.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2014
Kind
Unknown
Registered trials
29, 1 stopped early
Disease areas
Cancer; Urinary and reproductive; Pregnancy and women's health; Hormones; Skin and connective tissue; Digestive system

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Targets

GeneProteinUniProt
ANGPT2Angiopoietin-2O15123
ANGPT1Angiopoietin-1Q15389

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 1121200
Phase 2161311
Phase 31100
All trials29

Who ran its trials

CompanyRoleYears
AmgenLead sponsor of trials2005 to now
TakedaLead sponsor of trials2009 to now