Drug

Vabicaserin

As of the edition of 20 October 2026, Vabicaserin is a small molecule: went quiet in 2009; acts on HTR2A, HTR2B and HTR2C.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2009
Kind
Small molecule
Registered trials
9, 2 stopped early
Disease areas
Mental health

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

1 company-target row on route A because of this drug.

Companies on route A for this drug

In the product

1 company-target row is on route A because of Vabicaserin.

Targets

GeneProteinUniProt
HTR2A5-hydroxytryptamine receptor 2AP28223
HTR2C5-hydroxytryptamine receptor 2CP28335
HTR2B5-hydroxytryptamine receptor 2BP41595

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 16501
Phase 23201
All trials9

Who ran its trials

CompanyRoleYears
PfizerLead sponsor of trials2006 to now