Drug

Vadimezan

As of the edition of 20 October 2026, Vadimezan is a small molecule: stopped in 2020; acts on STING1.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2020
Kind
Small molecule
Registered trials
16, 8 stopped early
Disease areas
Cancer; Lungs and airways; Urinary and reproductive

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

2 companies on route A because of this drug.

Companies on route A for this drug

In the product

2 companies are on route A because of Vadimezan.

Target

GeneProteinUniProt
STING1Stimulator of interferon genes proteinQ86WV6

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 110505
Phase 24301
Phase 32002
All trials16

Who ran its trials

CompanyRoleYears
AntisomaLead sponsor of trials2003 to now
NovartisLead sponsor of trials2008 to now