Drug

Vorolanib

As of the edition of 20 October 2026, Vorolanib is a small molecule: in active development; acts on FLT1, FLT4 and KDR and 2 more.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Active, 2027
Kind
Small molecule
Registered trials
19, 2 stopped early
Disease areas
Cancer; Eye; Pregnancy and women's health; Urinary and reproductive; Lungs and airways; Hormones

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Targets

GeneProteinUniProt
PDGFRBPlatelet-derived growth factor receptor betaP09619
PDGFRAPlatelet-derived growth factor receptor alphaP16234
FLT1Vascular endothelial growth factor receptor 1P17948
FLT4Vascular endothelial growth factor receptor 3P35916
KDRVascular endothelial growth factor receptor 2P35968

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 14121
Phase 210441
Phase 35050
All trials19

Who ran its trials

CompanyRoleYears
EyePoint PharmaceuticalsLead sponsor of trials2021 to now
Betta PharmaceuticalsLead sponsor of trials2026 to now