Drug

Zerlasiran

As of the edition of 20 October 2026, Zerlasiran is an oligonucleotide: of no established status; acts on LPA.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Status not established
Kind
Oligonucleotide
Registered trials
1, 0 stopped early
Disease areas
Heart and blood vessels

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Target

GeneProteinUniProt
LPAApolipoproteinP08519

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 21100
All trials1

Who ran its trials

CompanyRoleYears
Silence TherapeuticsLead sponsor of trials2022 to now