Target

A2M

Alpha-2-macroglobulin

As of the edition of 20 October 2026, A2M (alpha-2-macroglobulin, UniProt P01023) has 1 drug tested at it and 2 companies on the list, 0 on route A and 0 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P01023
How well studied
Biology documented; no tool compounds or approved drug yet
Where it sits in the cell
Secreted
Solved structures
13

Drugs at this target

StatusCount
Marketed1
Total1
DrugStatusFurthest phaseUS protection
Technetium succimerMarketedNo phase statednone listed

1 of 1 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Undetermined2
Total on the list2