Target

DNMT3A

DNA

As of the edition of 20 October 2026, DNMT3A (DNA, UniProt Q9Y6K1) has 2 drugs tested at it and 7 companies on the list, 0 on route A and 4 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
Q9Y6K1
How well studied
Drug target: an approved drug acts on it
Where it sits in the cell
Inside the cell
Solved structures
47
Disease areas
Blood and lymph; Cancer; Immune system; Inherited and neonatal; Lungs and airways; Skin and connective tissue; Urinary and reproductive; Digestive system
Registered trials of its drugs
1,072

Drugs at this target

StatusCount
Marketed2
Total2
DrugStatusFurthest phaseUS protection
AzacitidineMarketedPhase 4Ends 2029
DecitabineMarketedPhase 4none listed

2 of 2 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route B4
Engaged2
Undetermined1
Total on the list7
Three companies on route A or B, with the route only
CompanyRoute
Bristol Myers SquibbRoute B
Johnson & JohnsonRoute B
Nippon ShinyakuRoute B

The other 4 companies at DNMT3A

In the product

7 companies in all; 4 are not named here, and no score is.

See the 7 companies at DNMT3A, ranked, with the facts behind eachRequest access. Nothing is shown until you do.