Target

F7

Coagulation factor VII

As of the edition of 20 October 2026, F7 (coagulation factor VII, UniProt P08709) has 3 drugs tested at it and 4 companies on the list, 1 on route A and 0 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P08709
How well studied
Chemical tools exist; no approved drug acts on it
Where it sits in the cell
Secreted
Solved structures
114
Disease areas
Blood and lymph; Inherited and neonatal; Cancer; Digestive system; Hormones
Registered trials of its drugs
3

Drugs at this target

StatusCount
Marketed1
Active1
Went quiet1
Total3
DrugStatusFurthest phaseUS protection
Factor ix complexMarketedPhase 1Ended 1982
HMB-001ActivePhase 2none listed
PCI-27483Went quietPhase 2none listed

3 of 3 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A1
Engaged1
Undetermined2
Total on the list4
Three companies on route A or B, with the route only
CompanyRoute
AbbVieRoute A

The other 3 companies at F7

In the product

4 companies in all; 3 are not named here, and no score is.

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