Target

GCGR

Glucagon receptor

As of the edition of 20 October 2026, GCGR (glucagon receptor, UniProt P47871) has 16 drugs tested at it and 18 companies on the list, 7 on route A and 3 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P47871
How well studied
Drug target: an approved drug acts on it
Where it sits in the cell
At a membrane
Solved structures
29
Disease areas
Nutrition and metabolism; Hormones; Immune system; Digestive system; Pregnancy and women's health; Urinary and reproductive; Inherited and neonatal; Nervous system
Registered trials of its drugs
256

Drugs at this target

StatusCount
Marketed4
Active3
Went quiet3
Stopped6
Total16
DrugStatusFurthest phaseUS protection
GlucagonMarketedPhase 4none listed
RetatrutideActivePhase 3none listed
SurvodutideActivePhase 3none listed
DasiglucagonMarketedPhase 3none listed
CotadutideStoppedPhase 2none listed
AdomeglivantStoppedPhase 2none listed
EfinopegdutideStoppedPhase 2none listed
VolagidemabActivePhase 2none listed
SAR425899StoppedPhase 2none listed
MK-0893Went quietPhase 2none listed
PF-06291874Went quietPhase 2none listed
Glucagon hydrochlorideMarketedPhase 3none listed

12 of 16 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A7
Route B3
Engaged3
Undetermined5
Total on the list18
Three companies on route A or B, with the route only
CompanyRoute
Eli LillyRoute B
PfizerRoute A
Merck & Co.Route A

The other 15 companies at GCGR

In the product

18 companies in all; 15 are not named here, and no score is.

See the 18 companies at GCGR, ranked, with the facts behind eachRequest access. Nothing is shown until you do.