Target

IL1A

Interleukin-1 alpha

As of the edition of 20 October 2026, IL1A (interleukin-1 alpha, UniProt P01583) has 2 drugs tested at it and 2 companies on the list, 1 on route A and 0 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P01583
How well studied
Chemical tools exist; no approved drug acts on it
Where it sits in the cell
In more than one place
Solved structures
4
Disease areas
Skin and connective tissue; Immune system; Infections; Inherited and neonatal; Bones, joints and muscles; Digestive system; Cancer; Blood and lymph
Registered trials of its drugs
32

Drugs at this target

StatusCount
Active1
Stopped1
Total2
DrugStatusFurthest phaseUS protection
BermekimabStoppedPhase 3none listed
LutikizumabActivePhase 3none listed

2 of 2 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A1
Engaged1
Total on the list2
Three companies on route A or B, with the route only
CompanyRoute
Johnson & JohnsonRoute A

The other 1 company at IL1A

In the product

2 companies in all; 1 is not named here, and no score is.

See the 2 companies at IL1A, ranked, with the facts behind eachRequest access. Nothing is shown until you do.