Target

IL1RL2

Interleukin-1 receptor-like 2

As of the edition of 20 October 2026, IL1RL2 (interleukin-1 receptor-like 2, UniProt Q9HB29) has 4 drugs tested at it and 5 companies on the list, 1 on route A and 0 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
Q9HB29
How well studied
Biology documented; no tool compounds or approved drug yet
Where it sits in the cell
At a membrane
Solved structures
4
Disease areas
Skin and connective tissue; Digestive system; Infections; Inherited and neonatal; Immune system
Registered trials of its drugs
47

Drugs at this target

StatusCount
Marketed1
Active1
Stopped2
Total4
DrugStatusFurthest phaseUS protection
SpesolimabMarketedPhase 4Ends 2034
ImsidolimabStoppedPhase 3none listed
HB0034ActivePhase 3none listed
REGN6490StoppedPhase 1none listed

4 of 4 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A1
Engaged1
Undetermined3
Total on the list5
Three companies on route A or B, with the route only
CompanyRoute
RegeneronRoute A

The other 4 companies at IL1RL2

In the product

5 companies in all; 4 are not named here, and no score is.

See the 5 companies at IL1RL2, ranked, with the facts behind eachRequest access. Nothing is shown until you do.