Target

MCAM

Cell surface glycoprotein MUC18

As of the edition of 20 October 2026, MCAM (cell surface glycoprotein MUC18, UniProt P43121) has 1 drug tested at it and 1 company on the list, 1 on route A and 0 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P43121
How well studied
Biology documented; no tool compounds or approved drug yet
Where it sits in the cell
At a membrane
Solved structures
1
Disease areas
Skin and connective tissue
Registered trials of its drugs
2

Drugs at this target

StatusCount
Went quiet1
Total1
DrugStatusFurthest phaseUS protection
ImaprelimabWent quietPhase 1none listed

1 of 1 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A1
Total on the list1
Three companies on route A or B, with the route only
CompanyRoute
Prothena BiosciencesRoute A

The other 0 companies at MCAM

In the product

1 company in all; 0 are not named here, and no score is.

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