Target

NGF

Beta-nerve growth factor

As of the edition of 20 October 2026, NGF (beta-nerve growth factor, UniProt P01138) has 7 drugs tested at it and 8 companies on the list, 7 on route A and 0 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P01138
How well studied
Chemical tools exist; no approved drug acts on it
Where it sits in the cell
In more than one place
Solved structures
10
Disease areas
Bones, joints and muscles; Nervous system; Inherited and neonatal; Urinary and reproductive; Pregnancy and women's health; Cancer; Hormones; Blood and lymph
Registered trials of its drugs
70

Drugs at this target

StatusCount
Went quiet3
Stopped3
Status not established1
Total7
DrugStatusFurthest phaseUS protection
TanezumabStoppedPhase 3none listed
FasinumabWent quietPhase 3none listed
FulranumabWent quietPhase 3none listed
MEDI7352StoppedPhase 2none listed
EP-9001AStatus not establishedPhase 1none listed
MEDI-578StoppedPhase 1none listed
PG-110Went quietPhase 1none listed

7 of 7 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A7
Undetermined1
Total on the list8
Three companies on route A or B, with the route only
CompanyRoute
PfizerRoute A
RegeneronRoute A
AstraZenecaRoute A

The other 5 companies at NGF

In the product

8 companies in all; 5 are not named here, and no score is.

See the 8 companies at NGF, ranked, with the facts behind eachRequest access. Nothing is shown until you do.