PDE8A
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A
As of the edition of 20 October 2026, PDE8A (high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A, UniProt O60658) has 1 drug tested at it and 2 companies on the list, 0 on route A and 0 on route B.
Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.
The protein
- UniProt
- O60658
- How well studied
- Drug target: an approved drug acts on it
- Solved structures
- 10
- Registered trials of its drugs
- 1
Drugs at this target
| Status | Count |
|---|---|
| Marketed | 1 |
| Total | 1 |
| Drug | Status | Furthest phase | US protection |
|---|---|---|---|
| Flavoxate | Marketed | Phase 1 | none listed |
1 of 1 drugs, the most tested first.
Companies at this target
| Where the company stands | Companies |
|---|---|
| Undetermined | 2 |
| Total on the list | 2 |