Target

SCN9A

Sodium channel protein type 9 subunit alpha

As of the edition of 20 October 2026, SCN9A (sodium channel protein type 9 subunit alpha, UniProt Q15858) has 61 drugs tested at it and 18 companies on the list, 4 on route A and 5 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
Q15858
How well studied
Drug target: an approved drug acts on it
Where it sits in the cell
In more than one place
Solved structures
44
Disease areas
Nervous system; Mental health; Injuries; Cancer; Bones, joints and muscles; Heart and blood vessels; Nutrition and metabolism; Urinary and reproductive
Registered trials of its drugs
2,714

Drugs at this target

StatusCount
Marketed44
Active5
Went quiet8
Stopped3
Withdrawn from market1
Total61
DrugStatusFurthest phaseUS protection
LidocaineMarketedPhase 4none listed
RopivacaineMarketedPhase 4none listed
TopiramateMarketedPhase 4none listed
LamotrigineMarketedPhase 4none listed
CarbamazepineMarketedPhase 4none listed
LacosamideMarketedPhase 4Ended 2026
RiluzoleMarketedPhase 4none listed
TetracaineMarketedPhase 4none listed
Eslicarbazepine acetateMarketedPhase 4Ended 2026
ZonisamideMarketedPhase 4none listed
PhenytoinMarketedPhase 4none listed
ArticaineMarketedPhase 4none listed

12 of 61 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A4
Route B5
Engaged8
Undetermined1
Total on the list18
Three companies on route A or B, with the route only
CompanyRoute
NovartisRoute B
BiogenRoute A
GSKRoute B

The other 15 companies at SCN9A

In the product

18 companies in all; 15 are not named here, and no score is.

See the 18 companies at SCN9A, ranked, with the facts behind eachRequest access. Nothing is shown until you do.