US protection ending in 2030: Eye
As of the edition of 20 October 2026, 15 drugs have US protection that ends in 2030 in eye; 10 of them have at least one company on route B because of it.
Sources: FDA Orange Book and Purple Book, other approval registers.
15 drugs
| Drug | US protection | Status | Holder | Target | Route B rows |
|---|---|---|---|---|---|
| Aceclidine | Ends 2030 (exclusivity) | Marketed | LENZ Therapeutics | 0 | |
| Acoltremon | Ends 2030 (exclusivity) | Marketed | Alcon | TRPM8 | 1 |
| Aflibercept | Ends 2030 (orphan exclusivity) | Marketed | Regeneron | PGF, VEGFA | 4 |
| Axitinib | Ends 2030 (patent) | Marketed | Pfizer | FLT1, FLT4, KDR | 0 |
| Cemiplimab | Ends 2030 (computed from the first US licence) | Marketed | Regeneron | PDCD1 | 2 |
| Cenegermin | Ends 2030 (computed from the first US licence) | Marketed | Dompé Farmaceutici | NTRK1, NTRK2, NTRK3 | 3 |
| Doxecitine | Ends 2030 (exclusivity) | Marketed | UCB | 0 | |
| Erenumab | Ends 2030 (computed from the first US licence) | Marketed | Amgen | CALCRL | 1 |
| Lifitegrast | Ends 2030 (patent) | Marketed | Bausch Health | ITGAL | 1 |
| Lotilaner | Ends 2030 (patent) | Marketed | Tarsus Pharmaceuticals | 0 | |
| Palovarotene | Ends 2030 (exclusivity) | Marketed | Ipsen | RARG | 1 |
| Pimavanserin | Ends 2030 (patent) | Marketed | Acadia Pharmaceuticals | HTR2A | 1 |
| Ravulizumab | Ends 2030 (computed from the first US licence) | Marketed | AstraZeneca | C5 | 0 |
| Sildenafil | Ends 2030 (exclusivity) | Marketed | Viatris | PDE5A | 3 |
| Trametinib | Ends 2030 (patent) | Marketed | Novartis | MAP2K1, MAP2K2 | 2 |
Listed by name. A route B row is one company at one target; for a drug with one target that is the number of companies. US protection is the US only, and it is not the date generics or biosimilars can enter.
Which companies are on route B in 2030 in eye
In the product10 of these 15 drugs have at least one company on route B. Which companies, and their scores, are in the product.
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