US protection ending in 2035: Digestive system
As of the edition of 20 October 2026, 18 drugs have US protection that ends in 2035 in digestive system, 17 of them marketed; 12 of them have at least one company on route B because of it.
Sources: FDA Orange Book and Purple Book, other approval registers.
18 drugs
| Drug | US protection | Status | Holder | Target | Route B rows |
|---|---|---|---|---|---|
| Bictegravir | Ends 2035 (patent) | Marketed | Gilead Sciences | 0 | |
| Brensocatib | Ends 2035 (patent) | Marketed | Insmed | CTSC | 1 |
| Brigatinib | Ends 2035 (patent) | Marketed | Takeda | ALK, EGFR | 1 |
| Cefiderocol | Ends 2035 (patent) | Marketed | Shionogi | 0 | |
| Efbemalenograstim alfa | Ends 2035 (computed from the first US licence) | Marketed | Evive Biotechnology | CSF3R | 2 |
| Ferric maltol | Ends 2035 (patent) | Marketed | Shield Tx | 0 | |
| Fruquintinib | Ends 2035 (patent) | Marketed | Takeda | FLT1, FLT4, KDR | 2 |
| Glecaprevir | Ends 2035 (patent) | Marketed | AbbVie | 0 | |
| Lenvatinib | Ends 2035 (patent) | Marketed | Eisai | FLT1, FLT4, KDR | 3 |
| Mirikizumab | Ends 2035 (computed from the first US licence) | Marketed | Eli Lilly | IL23A | 1 |
| Pafolacianine | Ends 2035 (patent) | Marketed | On Target | FOLR1 | 1 |
| Perflutren | Ends 2035 (patent) | Marketed | Lantheus Medical Imaging | 0 | |
| Pozelimab | Ends 2035 (computed from the first US licence) | Marketed | Regeneron | C5 | 1 |
| Retifanlimab | Ends 2035 (computed from the first US licence) | Marketed | Incyte | PDCD1 | 1 |
| Selinexor | Ends 2035 (patent) | Marketed | Karyopharm Therapeutics | XPO1 | 2 |
| Tasimelteon | Ends 2035 (patent) | Marketed | Vanda Pharmaceuticals | MTNR1A, MTNR1B | 2 |
| Toripalimab | Ends 2035 (computed from the first US licence) | Marketed | Coherus Oncology | PDCD1 | 2 |
| Umbralisib | Ends 2035 (patent) | Withdrawn from market | TG Therapeutics | ABL1, PIK3CD | 0 |
Listed by name. A route B row is one company at one target; for a drug with one target that is the number of companies. US protection is the US only, and it is not the date generics or biosimilars can enter.
Which companies are on route B in 2035 in digestive system
In the product12 of these 18 drugs have at least one company on route B. Which companies, and their scores, are in the product.
Get this list with the companies, scores and sources as a fileRequest access. Nothing is shown until you do.