Target

IL1R1

Interleukin-1 receptor type 1

As of the edition of 20 October 2026, IL1R1 (interleukin-1 receptor type 1, UniProt P14778) has 3 drugs tested at it and 3 companies on the list, 1 on route A and 0 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P14778
How well studied
Drug target: an approved drug acts on it
Where it sits in the cell
In more than one place
Solved structures
5
Disease areas
Immune system; Skin and connective tissue; Heart and blood vessels; Bones, joints and muscles; Infections; Lungs and airways; Cancer; Nutrition and metabolism
Registered trials of its drugs
147

Drugs at this target

StatusCount
Marketed1
Went quiet1
Stopped1
Total3
DrugStatusFurthest phaseUS protection
AnakinraMarketedPhase 4Ends 2027
AMG-108Went quietPhase 2none listed
MEDI-8968StoppedPhase 2none listed

3 of 3 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A1
Undetermined2
Total on the list3
Three companies on route A or B, with the route only
CompanyRoute
AstraZenecaRoute A

The other 2 companies at IL1R1

In the product

3 companies in all; 2 are not named here, and no score is.

See the 3 companies at IL1R1, ranked, with the facts behind eachRequest access. Nothing is shown until you do.