Drug

Adl-5747 free base

As of the edition of 20 October 2026, Adl-5747 free base is a small molecule: stopped in 2010; acts on OPRD1.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2010
Kind
Small molecule
Registered trials
2, 1 stopped early
Disease areas
Bones, joints and muscles; Nervous system

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

1 company on route A because of this drug.

Companies on route A for this drug

In the product

1 company is on route A because of Adl-5747 free base.

Target

GeneProteinUniProt
OPRD1Delta-type opioid receptorP41143

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 22101
All trials2

Who ran its trials

CompanyRoleYears
Merck & Co.Lead sponsor of trials2009 to now