Drug

Ondelopran

As of the edition of 20 October 2026, Ondelopran is a small molecule: went quiet in 2016; acts on OPRD1, OPRK1 and OPRM1.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2016
Kind
Small molecule
Registered trials
2, 0 stopped early
Disease areas
Chemically induced; Mental health

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

4 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

4 company-target rows are on route A because of Ondelopran.

Targets

GeneProteinUniProt
OPRM1Mu-type opioid receptorP35372
OPRD1Delta-type opioid receptorP41143
OPRK1Kappa-type opioid receptorP41145

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 21100
Phase 31100
All trials2

Who ran its trials

CompanyRoleYears
Eli LillyLead sponsor of trials2008 to now
R-PharmLead sponsor of trials2014 to now