Drug

Alicaforsen

As of the edition of 20 October 2026, Alicaforsen is an oligonucleotide: went quiet in 2018; acts on ICAM1.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Went quiet, 2018
Kind
Oligonucleotide
Registered trials
6, 0 stopped early
Disease areas
Digestive system

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

2 companies on route A because of this drug.

Companies on route A for this drug

In the product

2 companies are on route A because of Alicaforsen.

Target

GeneProteinUniProt
ICAM1Intercellular adhesion molecule 1P05362

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 11100
Phase 22200
Phase 33300
All trials6

Who ran its trials

CompanyRoleYears
Akcea TherapeuticsLead sponsor of trials2001 to now
Atlantic TherapeuticsLead sponsor of trials2015 to now