Target

ICAM1

Intercellular adhesion molecule 1

As of the edition of 20 October 2026, ICAM1 (intercellular adhesion molecule 1, UniProt P05362) has 3 drugs tested at it and 4 companies on the list, 4 on route A and 0 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P05362
How well studied
Chemical tools exist; no approved drug acts on it
Where it sits in the cell
At a membrane
Solved structures
14
Disease areas
Digestive system; Blood and lymph; Cancer; Immune system; Heart and blood vessels
Registered trials of its drugs
10

Drugs at this target

StatusCount
Went quiet1
Stopped2
Total3
DrugStatusFurthest phaseUS protection
AlicaforsenWent quietPhase 3none listed
BI-505StoppedPhase 2none listed
VP301StoppedPhase 1none listed

3 of 3 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A4
Total on the list4
Three companies on route A or B, with the route only
CompanyRoute
Atlantic TherapeuticsRoute A
Akcea TherapeuticsRoute A
Virtuoso BINcoRoute A

The other 1 company at ICAM1

In the product

4 companies in all; 1 is not named here, and no score is.

See the 4 companies at ICAM1, ranked, with the facts behind eachRequest access. Nothing is shown until you do.