Alprostadil
As of the edition of 20 October 2026, Alprostadil is a small molecule: marketed, first approved in 1982 (US); acts on PTGER1 and PTGER2; no US protection is listed.
Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.
The drug
- Status
- Marketed; latest approval 2014
- Kind
- Small molecule
- Brand name
- Prostin Vr Pediatric
- First approved
- 1 January 1982 (US)
- Approvals on record
- 31 in 6 regions
- Holder of the most recent approval
- Pfizer; 4 holders in all
- Registered trials
- 30, 6 stopped early
- Disease areas
- Heart and blood vessels; Urinary and reproductive; Pregnancy and women's health; Hormones; Eye; Inherited and neonatal
US protection
No US protection is listed.
The FDA registers list no drug-substance patent or exclusivity that counts for this drug.
This is the US only.
Companies that need a new molecule because of this drug
2 company-target rows on route B because of this drug.
Companies on route B for this drug
In the product2 company-target rows are on route B because of Alprostadil.
See the 2 company-target rows on route B for this drug, with the facts behind eachRequest access. Nothing is shown until you do.
Targets
Registered trials
| Phase | Trials | Completed | Active | Stopped early |
|---|---|---|---|---|
| Phase not stated | 4 | 3 | 0 | 0 |
| Phase 1 | 3 | 1 | 0 | 1 |
| Phase 2 | 8 | 2 | 0 | 2 |
| Phase 3 | 3 | 1 | 0 | 2 |
| Phase 4 | 12 | 5 | 0 | 1 |
| All trials | 30 |