Target

PTGER1

Prostaglandin E2 receptor EP1 subtype

As of the edition of 20 October 2026, PTGER1 (prostaglandin E2 receptor EP1 subtype, UniProt P34995) has 4 drugs tested at it and 8 companies on the list, 1 on route A and 1 on route B.

Sources: UniProt, ClinicalTrials.gov, ChEMBL, FDA Orange Book and Purple Book, Pharos.

The protein

UniProt
P34995
How well studied
Drug target: an approved drug acts on it
Where it sits in the cell
At a membrane
Solved structures
1
Disease areas
Urinary and reproductive; Heart and blood vessels; Pregnancy and women's health; Nutrition and metabolism; Hormones; Cancer; Digestive system; Eye
Registered trials of its drugs
78

Drugs at this target

StatusCount
Marketed2
Went quiet1
Status not established1
Total4
DrugStatusFurthest phaseUS protection
DinoprostoneMarketedPhase 4none listed
AlprostadilMarketedPhase 4none listed
ONO-8539Went quietPhase 2none listed
LimaprostStatus not establishedPhase 4none listed

4 of 4 drugs, the most tested first.

Companies at this target

Where the company standsCompanies
Route A1
Route B1
Undetermined6
Total on the list8
Three companies on route A or B, with the route only
CompanyRoute
PfizerRoute B
Ono PharmaceuticalRoute A

The other 6 companies at PTGER1

In the product

8 companies in all; 6 are not named here, and no score is.

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