Drug

Altiratinib

As of the edition of 20 October 2026, Altiratinib is a small molecule: stopped in 2018; acts on KDR, MET and NTRK1 and 3 more.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2018
Kind
Small molecule
Registered trials
1, 1 stopped early
Disease areas
Cancer

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

6 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

6 company-target rows are on route A because of Altiratinib.

Targets

GeneProteinUniProt
NTRK1High affinity nerve growth factor receptorP04629
METHepatocyte growth factor receptorP08581
KDRVascular endothelial growth factor receptor 2P35968
TEKAngiopoietin-1 receptorQ02763
NTRK3NT-3 growth factor receptorQ16288
NTRK2BDNF/NT-3 growth factors receptorQ16620

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 11001
All trials1

Who ran its trials

CompanyRoleYears
Deciphera PharmaceuticalsLead sponsor of trials2014 to now