Drug

Milciclib

As of the edition of 20 October 2026, Milciclib is a small molecule: stopped in 2018; acts on CDK1, CDK2 and CDK4 and 1 more.

Sources: FDA Orange Book and Purple Book, other approval registers, ClinicalTrials.gov, ChEMBL.

The drug

Status
Stopped, 2018
Kind
Small molecule
Registered trials
5, 2 stopped early
Disease areas
Cancer; Blood and lymph; Digestive system

US protection

No US approval on record.

With no US approval on record there are no listed US patents or exclusivities.

This is the US only.

Companies that need a new molecule because of this drug

4 company-target rows on route A because of this drug.

Companies on route A for this drug

In the product

4 company-target rows are on route A because of Milciclib.

Targets

GeneProteinUniProt
NTRK1High affinity nerve growth factor receptorP04629
CDK1Cyclin-dependent kinase 1P06493
CDK4Cyclin-dependent kinase 4P11802
CDK2Cyclin-dependent kinase 2P24941

Registered trials

PhaseTrialsCompletedActiveStopped early
Phase 11100
Phase 24102
All trials5

Who ran its trials

CompanyRoleYears
Nerviano Medical SciencesLead sponsor of trials2006 to now
Tiziana Life SciencesLead sponsor of trials2010 to now